NMN : MOST DIRECT NAD+ PRECURSOR

NMN stands for nicotinamide mononucleotide – a form of Vitamin B3 that occurs naturally in all living things. Your body uses NMN to produce NAD+, which every organism needs to survive. Because of its role as the raw ingredient for NAD+, NMN is what scientists call a ‘precursor' .
NMN is so critical to your health and wellbeing because it is the final step in the biological chain reaction that your body uses to make NAD+.

NAD+ can be produced through the “salvage pathway .”The salvage pathway of NAD+ biosynthesis uses naturally occurring compounds related to vitamin B3. These compounds include nicotinamide (NAM), nicotinic acid (NA), nicotinamide mononucleotide (NMN), and nicotinamide riboside (NR).

NAD+ biosynthesis in the salvage pathway involves NA conversion to NMN, whereas NR needs to be converted to NMN before transforming into NAD+ through the enzymatic activity of NMNAT. Supplementing with NMN allows skipping several steps to producing NAD+, which makes NMN the most direct NAD+ booster.

One of the key properties that positions NMN as an effective NAD+ booster is its potential speed of absorption into the body. Elevant Chief Scientist Dr. Alessia Grozio was part of a team that in 2019 published research which highlighted a key driver of NMN’s efficiency – a transporter that carries NMN directly into cells within minutes after ingestion

It was demonstrated that the Slc12a8 gene encodes a protein that is a specific NMN transporter in mammals. This protein uses a sodium ion to transport NMN (but not NR or NAM) across cell membranes and facilitates direct uptake of NMN into the gut and other organs.

There, biosynthesis and significantly increases NAD+ concentration in cells over the course of 60 minutes following ingestion. This indicates that NMN represents a direct entry point into the NAD+ synthesis pathway.

Common vegetables and fruits like broccoli, cabbages, and avocado contain small amounts of NMN. However, you need to consume 30 kilograms to sustain your required NMN levels.

Supplementing NMN delivers a steady amount of the raw ingredients your body needs to naturally boost NAD+ levels, helping you maintain critical elements of your health. ELEVANT PRIME, complete with high testing standards, can go a long way towards helping you achieve optimal health.

In a preclinical trial, scientists from the University of Oklahoma Health Sciences Center studying NMN supplementation find such supplementation improves brain and cognitive functions. NMN supplementation improves neurovascular coupling, a process whereby blood flow to the brain increases when neural activity increases. Improvement of neurovascular coupling, in turn, improves blood flow to the brain, correlating with enhanced brain function.

Immunity declines with age which impacts how your body reacts to infections or injuries. The changes in NAD levels influence essential cellular processes such as the immune response. Replenishing the level of NAD+ in your cells with NMN supplementation, re-charge energy levels required to fight back infection.

Over the past decade, research has shown the positive effects of NMN on healthy aging, improved longevity, and exercise performance. NMN supplementation enhances energy production and increases physical endurance by over 50%. Trials indicated that NMN taken orally by an adult could increase aerobic capacity — the consumption of oxygen by our muscles.